Larry, this is a great general discription, but the question I seek to answer is: has the expression distribution by each distinctin human cell type been identified for all known cell types and if so where can that wonderfully enlighting database be found? thanks. sterling At 03:48 PM 9/6/01 -0400, Larry Arnold wrote: > Maciej > > As far as I see it there is no argument to start. > > MHC stands for major histocompatibility c HLA stands for human >lymphocyte a "" "" All of the MHC molecules are codominant - i.e >all the genes are expressed- so each cell will express 6 MHC class I ( 2 >each of HLA-A,B,C) molecules and, on the appropriate cell types many class >II (HLA-D) molecules. > > Any basic immunology text will tell all of the above. > > Larry > > > At 06:56 PM 9/5/2001, you wrote: > I asked a few friends of mine who are in various (reputable) medical > When they took the 6 week course in > immunology as 2nd year students, they were told humans have MHC class > I and II. An immuno/microbio board review book I picked up at a > library also discusses MHC class I and II, in humans. So the > confusion is wide spread > > I don't want to start an argument, but I just thought I'd mention it. > > > Larry W. Arnold, Ph.D. > Res. Assoc. Prof. > Director, Flow Cytometry Facility > Department of Microbiology and Immunology > Lineberger Comprehensive Cancer Center > CB# 7290 > University of North Carolina at Chapel Hill > Chapel Hill, NC 27599 > Phone: 919-966-1530 > FAX: 919-962-8103 Computer Aided Cell and Molecular Biology (CACMB), not medicine, will find the cure for cancer and other diseases. There will always be a need for the trained clinician (MD/RN) but, advanced diagnostic and treatment option selection has become gene based, has moved from the physician's practice to the computerized cell and molecular biology laboratory, and appropriate treatment options should now be based on the personal biology of the patient.
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