Beads and apoptosis

From: Acquarola, Nick (Nick.Acquarola@health.wa.gov.au)
Date: Mon Aug 27 2001 - 21:18:28 EST

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Does anybody know whether the HLA-DQ molecule has any association with
apoptosis?
We use the Dynal Dynabeads to isolate B cells for microlymphocytoxicity
reactions and have noticed an abnormally higher (dead cell) background.
One thought put to me was that the beads attached to the DQ molecule may
initiate apoptosis.

Any thoughts?

Nick Acquarola

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