sizing micelles

From: Snezna Rogelj (snezna@nmt.edu)
Date: Sat Jun 16 2001 - 00:21:10 EST


Hello, this is probably one of those "stupid" questions that anyone in
posession of a flow cytometer should be ashamed to ask:

We would like to determine the size distribution of polymer/lipid micelles
which we can fluorescently stain with nile red. We have fluorescent beads
from Molecular Probes that are about 0.02um and about 1um in diameter to use
as size standards. We suspect the micelles to be somewhere around 0.5 um in
diamater. How do we go about translating the FSC readings to sub-microns? Is
it a linear parameter?

Thank you,

Snezna



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