Cell cycle vs poidy

From: joan Kalnitsky (jkalnits@vt.edu)
Date: Thu Jun 14 2001 - 07:11:04 EST


	I have a client who is interested in looking at the poidy level of her
megacaryocyte cell line.  The first time she came to the lab she brought
her samples and had used Vindelov's.  Her histograms looked just like cell
cycle histograms.  Not surprising as Vindelove's is used for cell cycle.
She admitted that when she had looked at ploidy levels years ago she did
not use Vindelov's, but did use a PI solution.
	Can anyone offer what PI protocol she should be using for poidy levels,
and if I should be approaching the set up of the Flow Cytometer in a
different manner than cell cycle work.	I have a client who looks at the
ploidy level of plants, but I know that they have to digest the plant
material first so I don't think their protocol would be appropriate for a
cell line.
	All input will be greatly appreciated, and as usual,
	Thanks in advance,
	Joan Kalnitsky


	Flow Cytometry Lab Supervisor
	VMRCVM
	(540) 231-4115
	FAX 540-231-7367
	jkalnits@vt.edu

	"It is better to serve than to receive."
	   B. Borg



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