Re: Fixation of Red Blood Cells

From: Arnold Pizzey (a.pizzey@UCL.ac.uk)
Date: Thu May 24 2001 - 02:18:15 EST


At 03:58 PM 5/22/01 -0400, you wrote:
>
>FLOWers
>
>	I am in need of a protocol to fix RBC's from mammalian species
>(other then human)
>
>	I would like to stabilize the antigens on the surface and then stain
>post fixation.
>
>Does anyone have any ideas
>
>Thank you for your time and attention
>
>Philip Barren
>
>
Greetings Philip,


I needed to do some surface/intracellular staining on RBCs a few months
ago. I tried the method of Davis et al from the 1998 transfusion paper
'Detection of fetal red cells in fetomaternal
hemorrhage using anti-hemoglobin F monoclonal antibody by flow cytometry
Transfusion, 38:749-756'
-Seemed to work ok for surface/intracellular staining

Best regards


Arnold



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	Arnold Richard Pizzey
	Department of Haematology
	Royal Free and University College London Medical School
	98 Chenies Mews
	London WC1E 6HX
	U.K

	voice:	+44 (0)20-7679-6234
	Fax:	+44 (0)20-7679-6222
	email:	a.pizzey@ucl.ac.uk
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