RBC fixatives

From: Bowden, Robert A MAJ WRAIR-Wash DC (Robert.Bowden@na.amedd.army.mil)
Date: Tue May 01 2001 - 14:40:18 EST


Dear all,
Does anyone have a protocol to fix human parasitized RBCs without losing any
of them?
I am attempting to surface stain RBCs with various antibodies, some pure,
some not.
I would like a protocol to fix them to stain them later or stain first and
read them later. What alterations in flow readings occur as a result of your
protocol?

I have just come across the 4% glucose addition to a 10% formaldehyde
preparation. However, this seems very harsh and they did not stain for
surface receptors.

best regards,

Bob Bowden



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