The CD4-/CD8-/alpha-betaTCR+ lymphocytes and other abnormal immunophenotypic findings typically seen in Autoimmune Lymphoproliferative Syndrome are described in Puck JM, Sneller MC. Seminars in Immunology 1997;9:77-84. We have had requests from clinicians to diagnose this, and have had two cases with the typical findings and another which was borderline.
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