Re: Autofluor

From: Saverio Alberti (alberti@alpha400.cmns.mnegri.it)
Date: Mon Jan 15 2001 - 08:30:39 EST


in an old paper (Cytometry 8: 114, 1987) we described a method of
cell-by-cell subtraction of autofluorescence using a straightforward
fluorescence channel compensation procedure. For flow analyses this is
useful and easy. In principle, you could do the same in a confocal
microscope by a point-by-point subtraction of an image taken in the red,
using green reagents.

Saverio Alberti
Head, Lab. of Experimental Oncology
Department of Cell Biology and Oncology
Consorzio Mario Negri Sud
66030 Santa Maria Imbaro (Chieti), Italy
Phone: (39-0872) 570.293
FAX: (39-0872) 570.412
E-mail: alberti@cmns.mnegri.it


On Fri, 12 Jan 2001, Joseph Mathew Antony wrote:

>
> Hi
>
> I have been having a problem with autofluorescence of fish tissues and
> cells. Does anybody know how to quench this? Suggestions will be warmly
> appreciated.....Cheers
> Joseph
> Joseph Mathew Antony
> Laboratory of Animal Health Biotechnology
> Institute of Molecular Agrobiology
> National University of Singapore
> 1 Research Link, Singapore 117604
>
> Tel: 8727472/8747474
> Fax: 8727518/8727007
> e mail: joseph@ima.org.sg
>	josephmatthew@hotmail.com
>	scip7297@nus.edu.sg
>
> " A journey of thousand miles begins with a single step " Confucious
>
> "You see things; and you say 'Why?'  But I dream things that
>  never were; and I say 'Why not?'" -- George Bernard Shaw
>
> "Science is a great game. It is inspiring and refreshing.The playing field
> is the universe itself" Isidor Isaac Rabi (US Physicist, Nobel Laureate 1944)
>
>



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