Re: Isolation of kupffer cells

From: Tom Mc Closkey (thomasm@nshs.edu)
Date: Wed Jun 28 2000 - 14:31:16 EST


arturo Colin Martinez wrote:
>
> I´m looking for information on how isolate kupffer cells from mouse´s liver
> and spleen. If any one can direct me to appropriate references and/or has
> any practical suggestions, I would greatly appreciate hearing from you.

	You might find the following reference useful:

Mc Closkey, TW, et al.	Lipopolysaccharide treatment of rats alters
antigen expression and oxidative metabolism in hepatic macrophages and
endothelial cells, Hepatology, 16: 191-203, 1992.


This work was done in a rat model system but describes Kupffer cell
isolation and the method should be similar.

Good luck,
Tom

*****************************************************************************
Thomas W. Mc Closkey, Ph. D.
Director of Flow Cytometry, North Shore University Hospital
Assistant Professor of Pediatrics, New York University School of
Medicine
Boas Marks Biomedical Research Center, 350 Community Drive
Manhasset, Long Island, New York 11030
ph:  516-562-4844 [office], 516-562-1135/4641 [lab]  fax:  516-562-2866
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