Re: Antibody to Wiskott-Aldrich Syndrome Protein

From: biocytex@biocytex.com
Date: Thu Sep 16 1999 - 10:49:44 EST


Richard McFarland asked
> Does anyoen know if a antibody to Wiskott-Aldrich Syndrome Protein (WASP)
> is commercially ( or non-commercially) available?

Richard,
I would suggest a look to the following paper : D.M. Stewart et al.,(1996)
Studies of the expression of the Wiscott-Aldrich Syndrome protein., J. Clin.
Invest., 97:2627-34.
WAS can also be investigated using quantitative flow cytometry on platelets.
In case you are interested in WASP, platelets and X-linked thrombocytopenia
(XLT), an other WAS disorder characterized by small platelet size, I suggest
you have a look to an interesting study of XLT presented at the last
I.S.T.H. meeting in Washington : N Schlegel, M-F Hurtaud-Roux, O Fenneteau,
C Kaplan. Is X-linked thrombocytopenia (XLT) a pure platelet variant of  WAS
?

Hope that helps.
Philippe Poncelet
Director,R&D
BioCytex
Marseille, France



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