Edoardo Colombo asked about a probe for studying the peripheral-type benzodiazepine receptor (PBR). Although I do not have a direct answer to the question for FGIN-1-27, I thought the following papers describing PBR labeling and quantitation with monoclonal antibody probes may be of interest to the topic : Dussossoy D. et al., Cytometry (1996),24:39-48 Carayon,P. et al., Blood (1996),87:3170-78. Hope that helps. Philippe Poncelet, PhD Director R&D Biocytex Marseille, France biocytex@biocytex.com ----- Message d'origine ----- De : Edoardo Colombo <edo.coledoco@tin.it> À : Cytometry Mailing List <cytometry@flowcyt.cyto.purdue.edu> Envoyé : vendredi 10 septembre 1999 11:49 Objet : benzodiazepine receptors by flow > > Hi Flowers, > is there anybody out there who is using a probe for the peripheral-type > benzodiazepine receptor (PBR) produced by Alexis called FGIN-1-27 (or > N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide) that Binds specifically > and with high affinity to the peptide benzodiazepine receptors and the new > fluorescent probe for the peripheral-type benzodiazepine receptor (PBR) > called NBD FGIN-1-27 Analog ? > Or someone who want to share with me an application protocol? > Thank you all > > Edoardo Colombo > Director Flow Lab > Dept. of Pathology > Valduce Hospital > Como, Italy > edo.coledoco@tin..it > > > >
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