Following Robin Allen's question, I would like to share with you what we heard from the last ISTH (International Society for Thrombosis and Hemostasis) meeting (Washington, August 14-21, 1999). Although the vW Collagen Binding Assay (vWCBA) is very reproducible, the results are dependent upon the origin and type of the collagen used in the test. Indeed, it seems that it explains why the type II von Willebrand diseases are usually misclassified with the vWCBA. Besides, I am personally glad that flow cytometry and especially quantitative flow cytometry is making such major steps into the field of hemostasis and thrombosis clinical diagnosis, being in this field since 1983 and in flow cytometry since 1994. We have a good fit there. With my best regards, Michel Canton, PharmD Managing Director BioCytex, France
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