Flow-ers, I am attempting to set-up studies on platelet activation and thrombogenicity of pharmacological agents. I would like to set-up an ACT test for clotting, but I was curious if anyone could advise me of any other tests that could be more applicable. For the platelet activation I was thinking of screening cells via flow cytometry for activation dependant glycoprotein expression i.e.. cd41a (IIb/IIIa), cd62p (p-selectin), etc. Does anyone have a protocol for these studies, and for the ACT test, that I may use? Thank you all in advance. Sameer Harish Scientist Guidant Corp. 3200 Lakeside Dr. Santa Clara, CA 95054 Mailing Address: PO Box 58167 Santa Clara, CA 95052 (Office) 408-235-3863 (Fax) 408-235-4074
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