Please circulate this among individuals looking for a first or second postdoc. Thanks! mr -------------------------------------------------- ANNOUNCEMENT: Two Postdoctoral positions are available at the University of California at San Francisco (UCSF): one to study lymphocyte dynamics in human disease, and the other to study the interaction of central and mucosal immunity in the setting of HIV disease. The first position is available June 1; the second position is available this fall. These positions provide an excellent opportunity to interact with a wide range of researchers and clinicians at UCSF and Stanford, apply the newest technologies to study important topics in both basic and clinical research, and ultimately to understand the immunopathogenesis of diseases. All in the setting of spectacular weather and an outstanding scientific environment! (1) Cellular immunology: We are studying the rich heterogeneity of peripheral lymphocytes using 10-color FACS, and are looking for a Postdoc to take a leading role in developing a detailed understanding of the functional and phenotypic characteristics of the more than 40 subsets of T cells, B cells, and NK cells found in peripheral blood. This Postdoc will design and implement experiments to study aspects of immune disregulation and reconstitution in the settings of bone marrow/stem cell transplantation, chemotherapy, and AIDS, in collaboration with clinical laboratories at Stanford and UCSF. An understanding of the principles of flow cytometry is preferred, as is experience with handling (infectious) human blood samples. An open mind, an ability to learn new technologies, and the desire to work in a highly collaborative environment are required. (2) Mucosal molecular immunology: Using a new tissue-based cell sorter (Laser Capture Microdissection), we are studying the mucosal immune responses to oral pathogens such as HPV, EBV, and Candida, principally in the setting of HIV disease. This study combines molecular immunology with cellular immunology to try to understand the interaction between the mucosal and central immune systems. The Postdoc who will lead these studies will have the opportunity to apply LCM, FACS, and molecular techniques to develop a coordinated view of the immune response to mucosal pathogens--work that will have significant impact for the development of knowledge and tools required to evaluate vaccine therapies for HIV and other viruses. Because of the novelty of the LCM technology, this is a wide-open field that presents an enormous opportunity to carve out a unique and important niche. Experience with molecular techniques (PCR, cloning, etc.) is necessary; a good understanding of mucosal immunology is desirable. An open mind, an ability to learn new technologies, and the desire to work in a highly collaborative environment are required. Interested students or postdocs should send an EMail or letter with a brief statement of research background and accomplishments and a curriculum vitae to: Mario Roederer Beckman B011 Stanford, CA 94305 Roederer@Stanford.Edu
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