Locating CK+ cells

From: Avis Peters (avispeters@netscape.net)
Date: Mon Apr 12 1999 - 11:42:45 EST


We are looking for CK+ cells in suspect cases of bone marrow, lymph nodes,
fine needle aspirates, and body fluids. At the present time we use Fix and
Perm and CK clone MNF116 - FITC. Our previous testing showed this to work
quite well for a test sample that was spiked with cytokeratin cells. But now
we have samples that are CD45 negative and immunohistochemically + for CK and
we can't consistently stain the CK+ cells by flow. Is there a better technique
that flow experts have found to work well?

avispeters@netscape.net
Avis Peters
United Hospital
St. Paul, MN
USA

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