Re: Kappa/lambda

From: Howard Ratech (ratech@aecom.yu.edu)
Date: Wed Feb 24 1999 - 15:28:50 EST


I would like to recommend to you a paper I wrote which discusses
statistical criteria for determining surface immunoglobulin light chain
restriction: 

Surface immunoglobulin light chain restriction in B-cell non-Hodgkin's
malignant lymphomas. H. Ratech and S. Litwin. Am J Clin Pathol 91:583-586,
1989.

Sincerely,

Howard Ratech, M.D.

On Wed, 24 Feb 1999, Chapple, Peter wrote:

> 
> There should be a simple answer to this question - but I just can't find it
> !.
> 
> What is the groups opinion on Kappa/Lambda and Lambda/Kappa ratios which are
> considered
> "consistent with monoclonality" ?? - in the clinical setting.
> 
> ie: K/L ratio >2.0 or 2.5 and how about L/K ?? This question is arising on a
> day to day basis around
> here and a reference would be really nice so that we can settle the
> arguement and get on with some
> work !!
> 
> Peter Chapple
> Melbourne AUSTRALIA 
> 



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