Dear Sirs There is some confusion in the mail list about this topic, I will explain it in a better way. I try to find information similar to Fidelio and Petrushka software from Coulter, but shareware. Of course, the system can be complemented with the cluster , discriminant or neural networks analysis, but this topic is secondary and besides there are excellent shareware software as Win Mdi (a good idea it would be join the expert system to Win Mdi). Other obvious need are the databases that were used for obtaining some results or some discriminant functions. Some years ago it was impossible to supply these databases in a printed journal, but today it is possible. Some virtual communities have understood this necessity and, for example, in StatLib, a web position about statistics algorithms, you can find the databases that were used in journals and books. In this way the results are REPRODUCIBLE. When you check the bibliography about discriminant functions, by example, you can find discussions and discussions. Because the databases are not available, one research obtains different results from other, although they use the same statistical procedures. Then, the questions begin: Others researches used patients very young? very old? did they round the numbers?. Besides, there is too much duplicate work. If you have a good idea about a statistical procedure you have to obtain 600 records again. If someone has these databases it is possible to create a free web position with these results and many researches can advance faster and cheaper. The source code of the shareware software can be included and so you avoid the black box syndrome of this software. Three important papers about this topic (but until I understand, they are not a shareware software) are: -Evaluation of a knowledge based system for interpreting flow cytometric inmunophenotyping data. Proceedings of MIB 93. Diamond, L et al.1993. pp 124-128 -Computer assisted bone marrow interpretation:A pattern approach. Proceedings of MIB 93. Nguyen, D et al. 1993. pp 119-123 - Localization of monoclonal B-cell populations through the use of Kolgomorov-Smirnov D-value and reduced Chi-square contours. Cytometry. Bagwell, C;Loven, EJ;Ault, KA. 1988. pp 469-476 Final note: In hematology there are many programs that were made decade after decade. Examples: ANEMIA, Context-I, HEME etc... If these systems are not commercial or they were abandonated, it would be a good idea that appeared in a web position. Best regards Carlos Quinones
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