With the goal to identify rare cancer cells in bodily fluids (blood, urine) we are currently experimenting with flow cytometry detection of telomerase mRNA and poly A+ mRNA in individual cells using in situ hybridization. To improve handling and in situ hybridization conditions we utilize our technology of cell encapsulation (cells are embedded in small, less than 50 um, gel microdrops). We are looking for collaborators from cancer clinics to obtain samples of blood or urine from healthy and ill individuals. We would like to apply for an SBIR grant and collaborators should provide consultations and expertise in the field of cancer (particularly blood cancers). Please reply to Jan Trnovsky PhD., Principal Scientist, One Cell Systems, Cambridge, MA
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