7-AAD staining

From: robert gniadecki (rgniadecki@hotmail.com)
Date: Thu Jan 14 1999 - 13:03:23 EST


Dear Cytometrists!

I am doing some 7AAD staining of lymphocytes for flow. I am not sure 
whether I should wash 7AAD out before analysis or keep the cells in 
7AAD. Strangely, keeping 7AAD increases background, but washing reduces 
DNA staining intensity. 

Is 7AAD's binding to DNA reversible and how stable it is?

What final concentration of 7AAD are you using?

Waiting impatiently for you response,

Robert Gniadecki
Dept. Dermatology, University of Copenhagen, Denmark


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