Nile Red and Aquatic Organisms

From: David Gebhard (gebhard@aecom.yu.edu)
Date: Tue Dec 16 1997 - 13:30:35 EST


Hello,  I am posting this as a favor to a friend not currently on
line.....please address any responses to me and I'll forward them on
thanks..... Dave G.

We are currently involved in efforts to measure lipid content in
single-cell marine organisms.  To achieve this, we would like to use Nile
Red, a stain that is soluble in acetone.  Our question is this-  Is there a
safe concentration of acetone that can be used to acheive a reasonable
signal in our biological sample that may be run on a FACScan?  Are there
alternative solvents that would be more forgiving to the FACScan plumbing?
Any helpful comments would be greatly appreciated!!
>
Dave Gebhard--Director FACS Facility
Albert Einstein College of Medicine
Chanin Building 309
1300 Morris Park Avenue
Bronx, New York 10461
718-430-2724/ 3573



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