Re: Kolmogorov-Smirnov

From: R Barclay (Robin_Barclay@compuserve.com)
Date: Tue Nov 25 1997 - 17:04:59 EST


Hello Ken
Re - degrees of freedom in calculating p from K-S stats . . . . .
>>Doing this will result in any two histograms
that are not identical being highly statistically significantly
different.  In other words using channels as degrees of freedom makes
the K-S test ridiculously too sensitive to trivial differences in the
histograms.<<
Empirically - I noticed this (overly sensitive) in BD's implementation in
CellQuest.  As I said in a previous post - I'm not too fond of just
accepting someone else's interpretation of a technique in implementing a
software package - hence wanting to get to the method for my own critical
interpretation.

>> I am sure there are others listening to this discussion who
are better qualified to discuss how one calculates degrees of freedom
for a flow histogram - I for one would be interested in such a
discussion.<<
Me too!  Please post/copy to me any discussion arriving directly to you
which is not copied to the Cytometry List (I will reciprocate).

Robin Barclay
SNBTS, Edinburgh
e-mail:Robin_Barclay@compuserve.com
Web: http://ourworld.compuserve.com/homepages/Robin_Barclay



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