re: apoptosis

From: C.Jacobs@NEFRO.AZN.NL
Date: Mon Nov 10 1997 - 09:13:53 EST


Hi Mayuni,

Try Dexamethason 1 uM to make your thymocytes apoptotic.
After 3  hour of culture about 30% of your thymocytes are 
Annexin V positive and PI negative. About 5% is positive for
both dyes.
When you do the incubation longer than 3 hr, you get more 
apoptotic cells. 
My suggestion is, make a time study an measure after every 
hour the annexinV / PI . After this you can make your choice
what time you use in the future.
Succes

Cor Jacobs
Department of Nephrology
University Hospital, Nijmegen
Nijmegen, the netherlands
E-Mail: C.jacobs@nefro.azn.nl



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