Autofluorescence and nodes

From: Drew Randall (drandall@cyllene.uwa.edu.au)
Date: Tue Oct 21 1997 - 17:31:04 EST


Hi, 
I am a very new flow operator and would appreciate any comments that might help me resolve my problem.  I recently had to analyse a piece of tumour tissue by flow.  My results suggest that the sample showed autofluorescence.  The original specimen was received in RPMI.  From this a cell suspension was prepared in PBS containing BSA and sodium azide.  After washing a number of times, the cells were stained, incubated and then analysed.  
I would appreciate any thoughts about my technique and/or the avoidance of this problem in the future.  
Thankyou in advance for any suggestions.
Wanda



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