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From: Maryalice Stetler-Stevenson (stetler@box-s.nih.gov)
Date: Fri Oct 10 1997 - 11:09:09 EST

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        I have a case that immunophenotypically looks like hairy cell
leukemia (monoclonal kappa, CD20 bright, CD22 bright, CD103+, CD11c+,
CD19+, FMC7 bright and negative for CD10, CD5,and CD23, however the CD25 is
negative). The peripheral blood smear looks like hairy cell. The clinician
from another institute reports the bone marrow, which I haven't seen,
doesn't look like hairy cell and the patient is not low in platelets. She
thinks it may be splenic marginal zone lymphoma. Has any one seen CD103+ on
a real splenic marginal zone lymphoma?

        Maryalice

Maryalice Stetler-Stevenson
Director Flow Cytometry Unit
Laboratory of Pathology, NCI, NIH

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