Re: Sorting on Slides

From: @icr.ac.uk@malin.icr.ac.uk
Date: Thu Sep 04 1997 - 12:31:19 EST


On Tue, 02 Sep 1997 13:13:59 -0400 (EDT) 
KDOMENICO@magnum.mco.edu wrote:
> 
> Hello everyone! I would like to ask those of you who sort on microscope slides 
> for histochemical stains or FISH for some technical help. We have tried sorting 
> ficolled cells onto slides using blood bank saline for the sheath fluid. The 
> sorting goes well but when the slides air dry atfer a sort, the cells lose 
> their integrity. Is there something else we should be doing? I have been trying 
> to monitor the bulletin board for other questions on this subject but have not 
> seen any as of yet. Thank you for your help.
> 
> Karen Domenico (a.k.a. The CCS Volunteer)
> Medical College of Ohio
> Toledo, Ohio
> 
> 
Use 1/10 saline as your sheath fluid. This will avoid 
problems caused by salt crystals as the sheath fluid 
evaporates.

I would also recommend using coated slides (I use 
polylysine but the SectionLock slides from Polysciences 
might be worth trying).

Michael Ormerod
preferred email address: Michael_Ormerod@compuserve.com



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