Dear Brad, I personally would like to put in my 2 cents regarding bone marrow analysis. First of all, good for you for responding the way you did! If more and more scientists or clinicians were humble enough to admit not knowing something, both patients and academicians would be better off! I especially congratulate Adrian for asking the same question I've been wanting to ask for the last few months. Bone marrow analysis is not as clear cut as examining peripheral blood and gating can be very tricky. 3-color analysis using markers that will discriminate LCA positive cells with low SSC from nucleated RBC and CD14 cells seems the best way to go. Anyway thankyou for the response and advice. Now I too feel I learned something and will not panic everytime I receive a bone marrow specimen. Thankyou! Francesca R. Giancotti, PhD.
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