Ca stores

From: sgaffin@NATICK-CCMAIL.ARMY.MIL
Date: Mon Apr 28 1997 - 08:22:02 EST


     Dear FLOWers,  I have an ACAS 570 and am having problems trying to 
     release Ca++ from internal stores, without having any Ca++ enter from 
     external solution in cultured endothelial cells.  Caffeine does not do 
     so.  Neither does ryanodine.  Thapsigargin gives equivocal results and 
     we need another agent.
     Does anyone have any suggestions for another agent?
     Thanks in advance,
        Steve Gaffin
     U.S. Army Research Institute of Environmental Medicine
     Natick MA 01760-5007
     Tel. 508-233-4867



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