PROLIFERATION

From: Woo, Gary (gary@amgen.com)
Date: Wed Apr 23 1997 - 17:06:01 EST


Dear flow people

does anyone have experience with a flow-based proliferation method that
doesn't require a lot of cells?  i'm looking to measure cytokine dose
response from cell lines.  the Brdu kits call for about a million cells
per test.  

ideally, i want to titer the cytokine and culture the cells in 96 well
microtiter plates, and seed  with 10E+03 or 10E+04 cells per well.  

greatly appreciate if anyone has a method that can measure cell prolif
with so few cells or an alternative to 96well plates that can give
standard curve information.

woo



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