Re: BrdU for measuring cell proliferation

From: Ioakim Spyridopoulos (ioakim@user1.channel1.com)
Date: Fri Apr 04 1997 - 19:24:08 EST


> From:          CAWAGN@MONSANTO.COM
> To:            Cytometry Mailing List <cytometry@flowcyt.cyto.purdue.edu>
> Subject:       Re: BrdU for measuring cell proliferation
> Date:          Thu, 3 Apr 1997 09:06:45 -0600

> 
> Hello,
> I need to measure the proliferation of a specific cell population
> (macrophages) and think that one of the bromo-deoxy-uridine and antibody
> kits would do the job.
> 
> Does anyone have any recommendations about which manufacturer's kit does a
> good job?  I have experienced variable quality in purchased kits, and
> would like to hear from someone who has actually used these before
> investing the money.  Thanks!
> 
> Rosemarie
> 
Dear Rosemarie,

you don't need a kit for that. I use 10 mM BrdU from SIGMA in the 
cell media and then the monoclonal BrdU antibody from Boehringer 
Mannheim to do a PI-BrdU doublestaining. It works very nice and their 
protocol is quite simple.

Ioakim Spyridopoulos, MD
Dept. of Cardiovascular Research
Boston, TUFTS University
email: ioakim@user1.channel1.com> 



This archive was generated by hypermail 2b29 : Wed Apr 03 2002 - 11:49:38 EST