I have been asked to put this message out - please reply to the address below not to me: Thank you. ------- Forwarded Message Follows ------- >From Louise Furukawa huge@itsa.ucsf.edu > Greetings from San Francisco. My name is Louise Furukawa and I am > post-doc at UCSF. I was referred to you by Enoc Hollemwegeuer at > Pharmingen. One of my projects has revolved around down-regulating MHC-I > on constituents on the vascular wall (endothelium, vascular smooth muscle > cells, and fibroblasts). We are able to do this well, and can show > decreased cytolysis of these so-modified endothelial cells by sensitized > lymphocytes. I'd like to demonstrate that the killing is specific for > MHC-I and am looking for an anti-MHC-I antibody that is directed to an > epitope essential for the CTL TCR/MHC-I interaction. Do you know of any > such antibody offhand or know of any article where they have done this? > I'd appreciate any leads. Thanks a lot. Louise -------------------------------------------------- J.Paul Robinson, Purdue University Cytometry Labs Professor of Immunopharmacology robinson@flowcyt.cyto.purdue.edu PH:317-494 6449 FAX:317-494 0517 web http://www.cyto.purdue.edu
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