Application:
Monoclonal antibody 2H11 reacts with a partially defined epitope of human thryoglobulin also present on thyroglobulins of mice and rats. It has a high affinity for the thyroglobulin molecule.
2H11 is applied in the localisation of thyroglobulin in hyperplastic and neoplastic thyroid. In addition, antibodies to thyroglobulin may be used to monitor patients after treatment for carcinoma of the follicular cells.
These antibodies can be applied in immunostaining on formalin-fixed paraffin embedded human.

Specifications:
Clone 2H11 produces mouse IgG1 immunoglobulins directed against thyroglobulin A typical working dilution in immunohistochemistry is 1:40

frozen sections	paraffin sections	flow cytometry	ELISA	Western Blotting
+	+	ND	ND	ND

Immunohistochemical staining for thyroglobulin in normal human thyroid using clone 2H11 (dia # 5).

References:
1 Ossendorp,FA., et al.,1989. J. Immunol. Meth. 120. 191-200
2 Ossendorp F.A., et al., 1989. Moll. Cell. Endocrinol. 66. 199-205
3 Ossendorp, F.A., et al., 1990. Endocrinol. 127. 419-430

For research only. Not for use in humans. For in vitro use only.