Application:
Polyclonal anti-kappa and anti-lambda antibodies can be applied in flow cytometry for analysis of blood samples. Rabbit anti-human kappa light chain is intended for use in flow cytometry and is available in combination with anti-human Lambda, with anti-CD19 or as a triple antibody i.e. anti-kappa plus anti-lambda plus anti-CD19. Anti-kappa and anti-lambda antibodies are frequently used in combination with anti-CD19 for the detection of light chains of surface immunoglobulin on normal and neoplastic B cells. These reagents are especially valuable in the study of the monoclonal nature (light chain restriction) of lymphoid neoplasms.

Specifications:
Anti-human kappa light chain polyclonal antibody is the F(ab')2 fragment of the purified immunoglobulin fraction of rabbit anti-serum.
Anti-human lambda light chain polyclonal antibody is the F(ab')2 fragment of the purified immunoglobulin fraction of goat anti-serum. These antibodies react with free light chains as well as intact immunoglobulin molecules.

References:
1. Stanworth, D.R., and Turner,W.W., 1987. In Handbook of Experimental Immunology, 3rd edition. Weir,D.M., eds. Blackwell Oxford.
2. Picker, L.J., et al., 1987, Am.J.Path., 128. 181

For research only. Not for use in humans. For in vitro use only.