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Flow cytometry is a rapid method for measuring the fluorescence and light scattering of individual cells in large numbers. By labelling the cells with fluorescent molecules that bind with high specificity to one particular cellular constituent it is possible to measure the content of the constituent. Such a fluorescent tag may be either a dye molecule with a high binding specificity for the particular component to be measured or a fluorescence-conjugated antibody. The light scattering of the cells gives information on their size and to some extent also on shape and structure.

In recent years flow cytometry has become an important tool in the studies of immune status of patients in a procedure called immunophenotyping. This is used in patients with leukaemia and some other malignant diseases, and any condition where the patients immune system is altered, e.g. HIV infection.

DAKO has built up a strong position in leukaemia typing and has a broad panel of products. The quality of DAKO's products have made them widely used in research laboratories as well as hospitals. Single, dual and triple colour reagents for flow cytometry are in the DAKO catalogue as well as calibration and data analysis software.

Through innovation DAKO can now offer the possibility of an easier way to prepare other body tissues, e.g. solid tumours for flow cytometry using the unique Medimachine for tissue disaggregation.

If you are interested to learn more about DAKO's flow cytometry products please contact your local DAKO sales office for a product catalogue or fill in the e-mail form on the Contact DAKO page.

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