Part Number: 7547105
TP Cathepsin-Rho110 was identified as a substrate for cathepsin C and cathepsin G by a screen of many different dipeptide derivatives. Cathepsin C (dipeptidyl-peptidase I, DPPI) is a lysosomal cysteine peptidase that is found in relative abundance in cytotoxic cells. Cathepsin G is a serine endopeptidase that is a major component of the azurophilic granules of polymorphonuclear leukocytes. Cathepsin G activity is high in promonocytic cells, but reduced in mature monocytes.
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