HLA-DR

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
B8.12.2	Purified	0.2 mg	Freeze-dried			IM0108
IgG2b (mouse)	Biotin	0.2 mg	Freeze-dried			IM0261
	Purified	100 tests	Liquid	IOTest		IM0462
	FITC	100 tests	Liquid	IOTest		IM0463
	PE	100 tests	Liquid	IOTest		IM0464
Immu-357	FITC	100 tests	Liquid	IOTest		IM1638
IgG1 (mouse)	PE	100 tests	Liquid	IOTest		IM1639
	PE-Cy5	100 tests	Liquid	IOTest		IM1849
H279 (I2)	Purified	100 tests	Freeze-dried	COULTER CLONE		6602142
IgG2a (mouse)	FITC	100 tests	Freeze-dried	COULTER CLONE		6602924
	RD1	100 tests	Liquid	COULTER CLONE		6602920
BL2	Purified	0.2 mg	Freeze-dried			IM0109
IgG2b (mouse)

The recognized epitope is a monomorphic determinant of human HLA class II molecules with estimated molecular weights of 29-34 kDa. These molecules are found on Antigen-Presenting Cells (APC), i.e. B lymphocytes, monocytes, macrophages, and thymic epithelial cells. They are also expressed on activated T cells, but not on granulocytes, platelets, and red blood cells. The I2 antigen is absent from some homozygous typing cells which are DR7+ or DR11+. Resting T cells or endothelial cells that do not normally express these molecules can be induced to express them. These molecules are involved in cellular interactions among immuno-competent cells. I2 antibody was evaluated during the Fifth International Workshop on Human Leukocyte Differentiation Antigens.

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