Map 4-Antibodies

Apoptotic Cells

Clone & Isotype Conjugate Size Format Part Number
2.7A6A3 (APO2.7) Purified 0.2 mg Freeze-dried IM2087
IgG1 (mouse) PE 100 tests Liquid IOTest IM2088
PE-Cy5 100 tests Liquid IOTest IM2089

The 2.7A6A3 antibody is reactive with an epitope exposed on apoptotic cells. The antigen defined by 2.7A6A3 (7A6 antigen) is a 38 kDa protein localized to the membrane of mitochondria and involved in the molecular cascade of apoptosis. The expression of 7A6 antigen is preferentially detected on apoptotic cells, but not on the normal cell surface or digitonin-permeabilized cells. It has been suggested that the expression of 7A6 antigen represents an early event of apoptosis rather than a final product of dead cells.
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