Map 4-Antibodies

Apoptosis MEBSTAIN Kit

Clone & Isotype Conjugate Size Format Line Part Number
Kit Avidin-FITC 40-66 tests IM1946

In cells in which apoptosis occurs, the chromatin DNA is cut by endonuclease at DNA-linked sites between nucleosomes resulting in a Number of multimers of nucleosomal DNA units in the nuclei.In the TUNEL method (TdT-mediated dUTP-biotin Nick End Labelling method developed by Gavrieli et al. (1992, J.Cell.Biol., vol. 119, 493-501)), 3'-OH DNA ends generated by DNA fragmentation is nick end labelled with biotinylated dUTP, mediated by terminal deoxynucleotidyl transferase (TdT), and then stained using avidin-conjugated FITC to allow specific staining. The MEBSTAIN Apoptosis kit is an apoptosis detection kit based on the TUNEL method.It is suitable for histochemistry (both frozen and paraffin-embedded tissue sections), cytospin preparations, and flow cytometry.
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