CD80

B-CELL SUBSET

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
MAB104	Purified	0.2 mg	Freeze dried			IM1449
IgG1 (mouse)	FITC	100 tests	Liquid	IOTest		IM1853
	PE	100 tests	Liquid	IOTest		IM1976

The CD80 antigen (B7, BB1) is a highly glycosylated single-chain protein. Its extracellular domain consists of two Ig-like domains. This 60 kDa molecule serves as the ligand for two structurally similar molecules expressed on T lymphocytes, CD28 and CTLA-4. CD80 antigen is expressed on in vitro activated B cells. It is not expressed on the majority of resting B cells from peripheral blood but identifies a subpopulation of B cells that has been previously activated. The antigen is also expressed by HTLV-1 transformed T cells.

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