CD62P (not available in USA)

P SELECTIN

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
CLBThromb/6	Purified	0.2 mg	Freeze-dried			IM1315
IgG1 (mouse)	Purified	100 tests	Liquid	IOTest		IM0767
	FITC	100 tests	Liquid	IOTest		IM1164
	PE	100 tests	Liquid	IOTest		IM1759

The CD62P antigen, also called LECAM-3 or P-selectin, is a 140 kDa molecule that mediates adhesion of neutrophil and monocyte to activated platelets and endothelial cells. It is expressed in the a-granules of the platelets and in the Weibel-Palade bodies of endothelial cells. Upon activation or thrombin stimulation, the antigen is translocated to the cell surface in both types of cells. Its ligands are PSGL-1 on granulocytes and CD34. CLBThromb/6 antibody recognizes an antigen preserved after platelet fixation. It inhibits platelet adhesion to eosinophils in cell adhesion assays. CLBThromb/6 antibody was evaluated during the Fifth International Workshop on Human Leukocyte Differentiation Antigens.

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