CD50

ICAM-3

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
HP2/19	Purified	0.2 mg	Freeze-dried			IM1600
IgG2a (mouse)	PE	100 tests	Liquid	IOTest		IM1601

The CD50 antigen is a 124 kDa molecule expressed by leukocytes and a wide variety of cells, but not by endothelial cells, platelets or erythrocytes. It is known as the InterCellular Adhesion Molecule-3 (ICAM-3) and interacts with LFA-1 in cellular adhesion. The HP2/19 antibody blocks adhesion which is directly or indirectly mediated by ICAM-3. This antibody is co-stimulating in CD3-dependent proliferation. HP2/19 antibody was evaluated during the Fifth International Workshop on Human Leukocyte Differentiation Antigens.

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