Map 4-Antibodies

CD46

MEMBRANE COFACTOR PROTEIN (MCP)

Clone & Isotype Conjugate Size Format Part Number
J4.48 Purified 0.2 mg Freeze-dried IM0846
IgG1 (mouse)

The CD46 antigen is a 66-56 kDa non-disulfide-linked dimeric protein with O-linked glycosylation. It is known as the Membrane Co-factor Protein (MCP), a cofactor which binds to C3b or C4b, allowing their degradation by a serine protease of the plasma, the factor I. It is expressed on thymocytes, T cells, B cells, monocytes, granulocytes, Natural Killer (NK) cells, platelets, endothelial cells, epithelial cells, fibroblasts, but not on erythrocytes. J4.48 antibody was evaluated during the Fourth International Workshop on Human Leukocyte Differentiation Antigens.
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