CD45RA

T-CELL SUBSET

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
2H4LDH11LDB9 (2H4)	Purified	100 tests	Freeze-dried	COULTER CLONE		6603121
IgG1 (mouse)	FITC	100 tests	Freeze-dried	COULTER CLONE		6603117
	RD1	100 tests	Liquid	COULTER CLONE		6603181
ALB11	Purified	0.2 mg	Freeze-dried			IM0537
IgG1 (mouse)	Purified	100 tests	Liquid	IOTest		IM0699
	FITC	100 tests	Liquid	IOTest		IM0584
	PE	100 tests	Liquid	IOTest		IM1834
CYTO-STATS

CD45RA epitopes are present on all the CD45 restricted molecules in which the A exon is expressed (ABC and AB containing isoforms). Most B lymphocytes express CD45RA isoforms.The various CD45 isoforms are differentially expressed on T cells having distinct functions. Peripheral T cells can be divided into two largely reciprocal populations of CD45RA- CD45RO+ and CD45RA+ CD45RO- cells. The inducer/suppressor subpopulations of CD4+ lymphocytes coexpress CD4 antigen and CD45RA isoforms. ALB11 antibody also reacts with B cells, monocytes and granulocytes. 2H4 antibody was evaluated during the Third International Workshop on Human Leukocyte Differentiation Antigens. ALB11 antibody was evaluated during the Fifth Workshop.

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