CD40

MATURE B CELLS

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
MAB89	Purified	0.2 mg	Freeze-dried			IM1374
IgG1 (mouse)	PE	100 tests	Liquid	IOTest		IM1936

The CD40 antigen is a glycosylated phosphoprotein. It is a member of the Tumor Necrosis Factor Receptor (TNFR) superfamily and contains four cysteine-rich repeats. Its molecular weight is about 44-48 kDa. It is present on all mature B lymphocytes, but not on plasma cells. It is strongly expressed by interdigitating cells and also by some epithelial cells and follicular dendritic cells. Co-culture with MAB89 and IL-4 leads to long term B cell proliferation.

---

---

© Coulter International Corporation, 1996. All rights reserved. Copyrights and Trademarks


Products are available FOR RESEARCH USE ONLY (RUO). Unless indicaed FOR IN VITRO DIAGNOSTIC USE (IVD)