CD33

MYELOID PRECURSORS

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
906 (MY9)	Purified	100 tests	Freeze-dried	COULTER CLONE		6602689
IgG2b (mouse)	FITC	100 tests	Freeze-dried	COULTER CLONE		6602985
	RD1	100 tests	Liquid	COULTER CLONE		6603042
D3HL60.251	Purified	100 tests	Liquid	IOTest		IM1134
IgG1 (mouse)	FITC	100 tests	Liquid	IOTest		IM1135
	PE	100 tests	Liquid	IOTest		IM1179
	PE-Cy5	100 tests	Liquid	IOTest		IM1955
CYTO-STATS

The CD33 antigen is a single-chain transmembrane glycoprotein with a molecular weight of 67 kDa. The extracellular portion of the molecule belongs to the Ig superfamily, involving one V-like and one C2-like domain. This antigen shows homology to myelin-associated glycoprotein and the CD22 molecule. It is expressed on monocytes in peripheral blood. In the bone marrow, CD33 antigen is found on granulocyte and macrophage precursors, and is absent from pluripotent stem cells. MY9 antibody was evaluated during the Second International Workshop on Human Leukocyte Differentiation Antigens. D3HL60.251 antibody was evaluated during the Fourth Workshop.

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