CD28

T-CELL SUBSET

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
4B10	FITC	0.5 mL	Liquid	COULTER		6607004
IgG1 (mouse)	RD1	0.5 mL	Liquid	COULTER		6607005
CD28.2	Purified	0.2 mg	Freeze-dried			IM1376
IgG1 (mouse)	Purified	100 tests	Liquid	IOTest		IM1235
	FITC	100 tests	Liquid	IOTest		IM1236
	PE	100 tests	Liquid	IOTest		IM2071

The CD28 antigen (Tp44) is a homodimer of disulfide-linked chains, with a molecular weight of 44 kDa each. It is expressed by a majority of CD3+ T cells. CD4+ T cells express the CD28 antigen more frequently than do CD8+ T cells. CD28 antigen is also present on plasma cells and thymocytes. This antigen is involved in the adhesion of T cells with B cells, through theB7/BB-1 glycoprotein (CD80) or through the B70/B7-2 glycoprotein (CD86). CD28.2 monoclonal antibody activates T cells.It cross-reacts with Rhesus monkey peripheral blood lymphocytes. CD28.2 antibody was evaluated during the Fifth International Workshop on Human Leukocyte Differentiation Antigens.

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