CD10

CALLA

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
J5	Purified	100 tests	Freeze-dried	COULTER CLONE		6602143
IgG2a (mouse)	FITC	100 tests	Freeze-dried	COULTER CLONE		6602463
	RD1	100 tests	Liquid	COULTER CLONE		6603475
ALB1	Purified	0.2 mg	Freeze-dried			IM0112
IgG1 (mouse)	PE	100 tests	Liquid	IOTest		IM1915
ALB2	Purified	0.2 mg	Freeze-dried			IM0113
IgG2a (mouse)	Purified	100 tests	Liquid	IOTest		IM0470
	FITC	100 tests	Liquid	IOTest		IM0471
CYTO-STATS

The CD10 antigen is refered to as the Common Acute Lymphoblastic Leukemia Antigen (CALLA). It is a type II integral membrane protein, identified as the human membrane-associated neutral endopeptidase, with a molecular weight of100 kDa. It is expressed on uncommitted lymphoid precursors. CD10 expression is lost as cells enter the T lineage. In theB lineage, CD10 expression is lost later, as cells acquire surface Ig expression. It is also expressed on activated and proliferating B cells in the germinal center and is found on neutrophils. J5 antibody was evaluated during the First International Workshop on Human Leukocyte Differentiation Antigens. ALB2 antibody was evaluated during the Third Workshop.

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