fate of cultured progenitors

Ralph Bohmer (ralph.bohmer@es.nemc.org)
Mon, 21 Jul 97 12:34:35 -24000

Could anyone help me find good references dealing the following subject:

Proliferating hemopoietic progenitors in culture (semi-solid or liquid)
differentiate to a certain point, then they get stuck and apoptose, I guess,
even with all relevant cytokines present (?)

How far do the cells from various lineages get ?
How do they die ?
How can death at this point be manipulated ?

Many thanks in advance

Ralph M. Bohmer
Mew England Medical Center