The case that you described (a child with an 11% population with a DNA index of
1.2) sounds remarkably similar to one that we reported in Cytometry (Communications
in Clinical Cytometry) 22:158, 1995.
Our conclusion in our case was that the child was demonstrating a false
DNA-aneuploidy (DI 1.2) due to an infection with EBV. Cytogenetic analysis was
normal and the EBV titer was 1:640 (capsid IgG) and 1:2 (nuclear antigen). We were
concerned that the EBV DNA within infected cells caused this increase in DNA
content.
Roy
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W. Roy Overton, Ph.D. overton@umdnj.edu
Assist. Professor of Pediatrics phone: 609-342-2894
Cooper Hospital/UMC fax: 609-338-0262
3 Cooper Plaza, Suite 410
Camden, NJ 08103 (USA)
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http://www4.umdnj.edu/~overton/cytometry.html