>From Louise Furukawa
huge@itsa.ucsf.edu
> Greetings from San Francisco. My name is Louise Furukawa and I am
> post-doc at UCSF. I was referred to you by Enoc Hollemwegeuer at
> Pharmingen. One of my projects has revolved around down-regulating MHC-I
> on constituents on the vascular wall (endothelium, vascular smooth muscle
> cells, and fibroblasts). We are able to do this well, and can show
> decreased cytolysis of these so-modified endothelial cells by sensitized
> lymphocytes. I'd like to demonstrate that the killing is specific for
> MHC-I and am looking for an anti-MHC-I antibody that is directed to an
> epitope essential for the CTL TCR/MHC-I interaction. Do you know of any
> such antibody offhand or know of any article where they have done this?
> I'd appreciate any leads. Thanks a lot. Louise
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J.Paul Robinson, Purdue University Cytometry Labs
Professor of Immunopharmacology
robinson@flowcyt.cyto.purdue.edu PH:317-494 6449 FAX:317-494 0517
web http://www.cyto.purdue.edu