>
> An investigator read somewhere(?) of a panel of monoclonal Abs used
> to identify murine progenitor/stem cells. Of interest is an antibody called
> "lin-neg." Anyone out there heard of it before/know of it's source? It
> sounds like it might be a cocktail of different Abs.
> Thanks,in advanced, to all responses.
>
Lin neg refers to a variety of antibody cocktails or sequential antibody
screens to assure that a putative "stem cell" does not express any
surface antigen felt to denote lineage committment eg CD33, CD19, CD3.
Steve Gore
Johns Hopkins Oncology Center